International Review of Ophthalmology

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Research progress on morphology and associations of tilted optic disc

FAN Yuan-yuan, WEI Wen-bin   

  1. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing 100730, China
  • Received:2016-03-30 Online:2016-04-22 Published:2016-04-22
  • Contact: WEI Wen-bin, Email: weiwenbintr@163.com
  • Supported by:

    National Natural Science Foundation of China (81570891，81272981); Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (ZYLX201307)； Beijing Natural Science Foundation (7151003); Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau ( 2014-2-003)

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Abstract:

Tilted optic disc is defined as one edge of the optic disc elevates in the horizontal or vertical axis. Tilted optic disc is not rare in population. The abnormal “tilted” appearance brings difficulty not only in clinical measurement analysis such as parapapillary neural retinal fiber layer (RNFL) and choroidal thickness but also confuses visual field results interpretation. Orientation and extent of optic disc tilt may correlated with glaucoma and myopia. Study on quantitative analysis of optic disc tilt angle could evaluate optic disc morphology accurately and help correcting measurement error in parapapillary structures. Quantitative measurement and prospective studies of optic disc tilt angle are helpful for research on the pathogenesis of glaucoma and myopia. It also provided basic of scientific research and clinical biomarker for monitoring related disease progression.  (Int Rev Ophthalmol,  2016,  40:  73-80)